Basics of Systematic Reviews

A guide to evidence synthesis

Step 3b: Searching Grey Literature

In order to perform a comprehensive search of the available literature, you should also search grey literature.  Grey literature is research and other types of information produced outside of academic or traditional publishing channels like scientific journals.  Examples of grey literature include:

Completed clinical trials Research studies that test a medical, surgical, or behavioral intervention in people.  
 
Conference Proceedings (can include posters & papers)
Government Reports International, national, and local governmental documents.
Preprints A full draft of a research paper that is shared publicly before it has been peer reviewed.
Statistical Data Often considered grey literature as they are published by government, research organizations and researchers, not by traditional publishing sources.
White Papers A research-based report that examines a topic and offers potential solutions to a problem.
Guidelines and Position Papers Issued by organizations (such as American Cancer Society) produced outside of traditional publishing and distribution channels.

There are a number of places you can search for grey literature, including:

Step 3c: Applying PRISMA

There are guidelines available for suggested reporting items when documenting your search in the written portion of your review.  For this step, review the PRISMA-S checklist, which is the search reporting extension of PRISMA.  Make sure to specify the dates when each resource was last searched.  It's important to document the full search strategy used in each database, register, or website.  Any applied limiters and filters should be documented as well and included in an appendix.