Basics of Systematic Reviews

A guide to evidence synthesis

Step 2a: Develop a Protocol

A protocol is a detailed plan that outlines the design of your systematic review.  Never start the searching process before creating a protocol.  When writing a protocol, you will:

  • Describe the rationale/objectives for conducting the systematic review
  • List the PI and team members
  • Define the eligibility criteria you'll use to screen the literature
  • Decide which databases you'll be searching
  • Key terms that will be used in the literature search (ideally, a full search strategy for at least 1 database).
  • Explain if you're searching both published and unpublished literature (and grey literature)
  • Explain how you'll be extracting data from eligible articles.
    • Data items that will be extracted.
  • Describe the quality assessment tool(s) you'll use to evaluate the literature.

Finally, you'll upload your protocol to a registry to make it publicly available.

Step 2a (continued): Use PRISMA-P to Write the Protocol

While the PRISMA 2020 Checklist (as mentioned in the Pre-Review Tasks) describes the components you should include in the review, the PRISMA-P checklist contains 17 items that are considered essential components of a protocol.  You can review and download the PRISMA-P checklist for protocols below:

Step 2b: Make your Protocol Visible

In the spirit of transparency and reproducibility, core tenets of Open Science practices, you should make your protocol visible and available to others by uploading it to a registry.  If you plan to publish your protocol in a journal, make sure to check the protocol requirements on the journal website before submitting.

Where to register your systematic review protocol:

Protocol Templates

https://library.ccny.cuny.edu/PublicHealth/litreviews